Invention Grant
US09028816B2 Polypeptides and polypeptide constructs comprising single domain antibodies directed against von Willebrand factor
有权
包含针对von Willebrand因子的单结构域抗体的多肽和多肽构建体
- Patent Title: Polypeptides and polypeptide constructs comprising single domain antibodies directed against von Willebrand factor
- Patent Title (中): 包含针对von Willebrand因子的单结构域抗体的多肽和多肽构建体
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Application No.: US10541708Application Date: 2004-01-09
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Publication No.: US09028816B2Publication Date: 2015-05-12
- Inventor: Karen Silence
- Applicant: Karen Silence
- Applicant Address: BE Zwijnaarde
- Assignee: Ablynx N.V.
- Current Assignee: Ablynx N.V.
- Current Assignee Address: BE Zwijnaarde
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: EP03447005 20030110
- International Application: PCT/BE2004/000002 WO 20040109
- International Announcement: WO2004/062551 WO 20040729
- Main IPC: A61K39/395
- IPC: A61K39/395 ; G01N33/86 ; A61K38/16 ; A61K38/49 ; C07K16/18 ; C07K16/28 ; C07K16/36 ; A61K39/00
Abstract:
The present invention relates to polypeptides and polypeptide constructs comprising at least one single domain antibody directed against vWF, vWF A1 domain, A1 domain of activated vWF, vWF A3 domain, homologues of said polypeptides, and/or functional portions of said polypeptides, for the treatment for conditions which require a modulation of platelet-mediated aggregation.
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