Invention Grant
- Patent Title: Humanized anti-EGFR antibody L4-H3 and coding gene thereof
- Patent Title (中): 人源化抗EGFR抗体L4-H3及其编码基因
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Application No.: US13982173Application Date: 2011-03-25
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Publication No.: US09028832B2Publication Date: 2015-05-12
- Inventor: Yanwen Jin , David Weaver , Michael Rynkiewicz , Cheng Cao
- Applicant: Yanwen Jin , David Weaver , Michael Rynkiewicz , Cheng Cao
- Applicant Address: CN HeFei, AnHui Province
- Assignee: HeFei Tairui Biotechnology Co., Ltd.
- Current Assignee: HeFei Tairui Biotechnology Co., Ltd.
- Current Assignee Address: CN HeFei, AnHui Province
- Agency: Knobbe Martens Olson & Bear LLP
- Priority: CN201110029453 20110127
- International Application: PCT/CN2011/000501 WO 20110325
- International Announcement: WO2012/100384 WO 20120802
- Main IPC: C07K16/00
- IPC: C07K16/00 ; A61K39/395 ; C07K16/30 ; C07K16/28
Abstract:
A humanized anti-EGFR antibody L4-H3 and gene encoding the antibody are disclosed. The antibody is composed of a heavy chain and a light chain. The amino acid sequence of the heavy chain variable region is shown as positions 1-145 of SEQ ID NO: 3, the heavy chain constant region is the heavy chain constant region of the human antibody IgG1, and the amino acid sequence of the light chain is shown as SEQ ID NO: 1.
Public/Granted literature
- US20130330362A1 HUMANIZED ANTI-EGFR ANTIBODY L4-H3 AND CODING GENE THEREOF Public/Granted day:2013-12-12
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