Invention Grant
- Patent Title: Hydrogel-driven drug dosage form
- Patent Title (中): 水凝胶驱动药物剂型
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Application No.: US12979278Application Date: 2010-12-27
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Publication No.: US09028870B2Publication Date: 2015-05-12
- Inventor: Leah E. Appel , Ronald A. Beyerinck , Mark B. Chidlaw , William J. Curatolo , Dwayne T. Friesen , Kelly L. Smith , Avinash G. Thombre
- Applicant: Leah E. Appel , Ronald A. Beyerinck , Mark B. Chidlaw , William J. Curatolo , Dwayne T. Friesen , Kelly L. Smith , Avinash G. Thombre
- Applicant Address: US OR Bend
- Assignee: Bend Research, Inc.
- Current Assignee: Bend Research, Inc.
- Current Assignee Address: US OR Bend
- Agency: Klarquist Sparkman, LLP
- Main IPC: A61K9/00
- IPC: A61K9/00
Abstract:
A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The drug-containing composition comprises a low-solubility drug and a drug-entraining agent. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of formulations having specific drug release profiles are disclosed.
Public/Granted literature
- US20110182947A1 HYDROGEL-DRIVEN DRUG DOSAGE FORM Public/Granted day:2011-07-28
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