Invention Grant
US09028878B2 Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
有权
铋硫醇作为生物医学用途的防腐剂，包括细菌生物膜的处理和其他用途
- Patent Title: Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
- Patent Title (中): 铋硫醇作为生物医学用途的防腐剂，包括细菌生物膜的处理和其他用途
-
Application No.: US13566816Application Date: 2012-08-03
-
Publication No.: US09028878B2Publication Date: 2015-05-12
- Inventor: Brett Hugh James Baker
- Applicant: Brett Hugh James Baker
- Applicant Address: US MT Bozeman
- Assignee: Microbion Corporation
- Current Assignee: Microbion Corporation
- Current Assignee Address: US MT Bozeman
- Agency: Seed IP Law Group PLLC
- Main IPC: A01N59/02
- IPC: A01N59/02 ; A61K9/00 ; A61K9/06 ; A61K9/10 ; A61K9/70 ; A61K31/095 ; A61K31/29 ; A61K33/24
Abstract:
Compositions and methods, including novel homogeneous microparticulate suspensions, are described for treating natural surfaces that contain bacterial biofilm, including unexpected synergy or enhancing effects between bismuth-thiol (BT) compounds and certain antibiotics, to provide formulations including antiseptic formulations. Previously unpredicted antibacterial properties and anti-biofilm properties of disclosed BT compounds and BT compound-plus-antibiotic combinations are also described, including preferential efficacies of certain such compositions for treating certain gram-positive bacterial infections, and distinct preferential efficacies of certain such compositions for treating certain gram-negative bacterial infections.
Public/Granted literature
Information query
