A method for detecting analyte in a sample comprises: (a) contacting said sample with at least one set comprising a cassette oligonucleotide and first, second, third and fourth proximity probes, which probes each comprise an analyte-binding domain and a nucleic acid domain and can simultaneously bind to the analyte, the nucleic acid domains of said first and third proximity probes being complementary in a first overlap region and the nucleic acid domains of said second and fourth proximity probes being complementary in a second overlap region; and said cassette oligonucleotide being complementary to the nucleic acid domain of said third proximity probe in a third overlap region and to the nucleic acid domains of said fourth proximity probe in a fourth overlap region; (b) allowing the overlap regions of said proximity probes and said cassette oligonucleotide to hybridise; and (c) detecting said hybridisation. A kit is for performing the method.