Invention Grant
- Patent Title: Analytical methods for analyzing and determining impurities in dianhydrogalactitol
- Patent Title (中): 分析和测定二缩水甘油醇中杂质的分析方法
-
Application No.: US14083135Application Date: 2013-11-18
-
Publication No.: US09029164B2Publication Date: 2015-05-12
- Inventor: Xiaoyun Lu , Mike Tso-Ping Li
- Applicant: Del Mar Pharmaceuticals
- Applicant Address: CA Vancouver
- Assignee: Del Mar Pharmaceuticals
- Current Assignee: Del Mar Pharmaceuticals
- Current Assignee Address: CA Vancouver
- Agency: Ditthavong Mori & Steiner, P.C.
- Main IPC: G01N33/15
- IPC: G01N33/15 ; G01N21/49 ; G01N30/88
Abstract:
An improved analytical method for analysis of dianhydrogalactitol preparations provides a method for determining the purity of dianhydrogalactitol and detecting impurities in preparations of dianhydrogalactitol, as well as identifying any such impurities. The method employs high performance liquid chromatography (HPLC), in particular, HPLC with evaporative light scattering detection (ELSD); the HPLC can be followed by tandem mass spectroscopy. The method can further comprise the step of performing preparative HPLC collection of at least one specific substance peak present in a preparation of dianhydrogalactitol.
Public/Granted literature
- US20140315318A1 ANALYTICAL METHODS FOR ANALYZING AND DETERMINING IMPURITIES IN DIANHYDROGALACTITOL Public/Granted day:2014-10-23
Information query
