Invention Grant
US09029168B2 Use and making of biosensors utilizing antimicrobial peptides for highly sensitive biological monitoring
有权
使用和制作利用抗菌肽的生物传感器进行高度敏感的生物监测
- Patent Title: Use and making of biosensors utilizing antimicrobial peptides for highly sensitive biological monitoring
- Patent Title (中): 使用和制作利用抗菌肽的生物传感器进行高度敏感的生物监测
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Application No.: US13171120Application Date: 2011-06-28
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Publication No.: US09029168B2Publication Date: 2015-05-12
- Inventor: Michael C. McAlpine , Manu Sebastian Mannoor
- Applicant: Michael C. McAlpine , Manu Sebastian Mannoor
- Applicant Address: US NJ Princeton
- Assignee: The Trustees of Princeton University
- Current Assignee: The Trustees of Princeton University
- Current Assignee Address: US NJ Princeton
- Agency: Meagher Emanuel Laks Goldberg & Liao, LLP
- Main IPC: G01N33/543
- IPC: G01N33/543 ; G01N27/12 ; B82Y15/00 ; B82Y30/00

Abstract:
A biosensor and method of making are disclosed. The biosensor is configured to detect a target and may include a peptide immobilized on a sensing component, the sensing component having an anode and a cathode. The immobilized peptide may comprise an antimicrobial peptide binding motif for the target. The sensing component has an electrical conductivity that changes in response to binding of the immobilized peptide to the target. The immobilized peptide may bind one or more targets selected from the list consisting of: bacteria, Gram-negative bacteria, Gram-positive bacteria, pathogens, protozoa, fungi, viruses, and cancerous cells. The biosensor may have a display with a readout that is responsive to changes in electrical conductivity of the sensing component. The display unit may be wirelessly coupled to the sensing component. A resonant circuit with an inductive coil may be electrically coupled to the sensing component. A planar coil antenna may be disposed in proximity to the resonant circuit, the planar coil antenna being configured to provide power to the sensing component.
Public/Granted literature
- US20120156688A1 USE AND MAKING OF BIOSENSORS UTILIZING ANTIMICROBIAL PEPTIDES FOR HIGHLY SENSITIVE BIOLOGICAL MONITORING Public/Granted day:2012-06-21
Information query
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