Invention Grant
- Patent Title: Glycopegylated granulocyte colony stimulating factor
- Patent Title (中): 糖基化的粒细胞集落刺激因子
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Application No.: US11794560Application Date: 2006-01-10
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Publication No.: US09029331B2Publication Date: 2015-05-12
- Inventor: Shawn DeFrees , Henrik Clausen , David A. Zopf , Caryn Bowe , Susann Taudte , Michael Felo , Walter S. Willett
- Applicant: Shawn DeFrees , Henrik Clausen , David A. Zopf , Caryn Bowe , Susann Taudte , Michael Felo , Walter S. Willett
- Applicant Address: DK Bagsvaerd
- Assignee: Novo Nordisk A/S
- Current Assignee: Novo Nordisk A/S
- Current Assignee Address: DK Bagsvaerd
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2006/000870 WO 20060110
- International Announcement: WO2006/074467 WO 20060713
- Main IPC: A61K38/14
- IPC: A61K38/14 ; A61K38/16 ; A61K38/22 ; C07K14/575 ; C07K14/535 ; C07K1/18 ; C07K1/107 ; A61K47/48 ; A61K38/00
Abstract:
The invention relates to methods of preparing and purifying conjugates between Granulocyte Colony Stimulating Factor and PEG moieties. The conjugates are linked via an intact glycosyl linking group that is interposed between and covalently attached to the peptide and the modifying group. The conjugates are purified using various chromatography methods.
Public/Granted literature
- US20090203579A1 Glycopegylated Granulocyte Colony Stimulating Factor Public/Granted day:2009-08-13
Information query
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