Invention Grant
- Patent Title: Substituted benzamide derivatives
- Patent Title (中): 取代苯甲酰胺衍生物
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Application No.: US13485993Application Date: 2012-06-01
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Publication No.: US09029370B2Publication Date: 2015-05-12
- Inventor: Guido Galley , Roger Norcross , Philippe Pflieger
- Applicant: Guido Galley , Roger Norcross , Philippe Pflieger
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Priority: EP11169441 20110610
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D413/14 ; C07D265/30 ; C07D413/12

Abstract:
The present invention relates to compounds of formula wherein R1, R2, R3, X, Z, Ar, and n are as described in the claims, Ar is phenyl or heteroaryl, selected from the group consisting of 1H-indazole-3yl, pyridine-2-yl, pyridine-3-yl, pyridine-4-yl, pyrimidine-5-yl, 1H-pyrazole-3-yl, 1H-pyrazole-4-yl and 1H-pyrazole-5-yl; or to a pharmaceutically suitable acid addition salt thereof, which may be used for the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, migraine, hypertension, substance abuse, metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
Public/Granted literature
- US20120316165A1 SUBSTITUTED BENZAMIDE DERIVATIVES Public/Granted day:2012-12-13
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