Invention Grant
US09029405B2 5-(biphenyl-4-yl)-3-phenyl-1,2,4-oxadiazolyl derivatives as ligands on the sphingosine 1-phosphate(SIP)receptors
有权
5-（联苯-4-基）-3-苯基-1,2,4-恶二唑基衍生物作为鞘氨醇1-磷酸（SIP）受体上的配体
- Patent Title: 5-(biphenyl-4-yl)-3-phenyl-1,2,4-oxadiazolyl derivatives as ligands on the sphingosine 1-phosphate(SIP)receptors
- Patent Title (中): 5-（联苯-4-基）-3-苯基-1,2,4-恶二唑基衍生物作为鞘氨醇1-磷酸（SIP）受体上的配体
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Application No.: US13809013Application Date: 2011-07-06
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Publication No.: US09029405B2Publication Date: 2015-05-12
- Inventor: Agnes Bombrun , Anna Quattropani , Jerome Gonzalez , Jerome Dorbais , Chris Knight , Charles Baker-Glenn
- Applicant: Agnes Bombrun , Anna Quattropani , Jerome Gonzalez , Jerome Dorbais , Chris Knight , Charles Baker-Glenn
- Applicant Address: CH Coinsins
- Assignee: Merck Serono S.A.
- Current Assignee: Merck Serono S.A.
- Current Assignee Address: CH Coinsins
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: EP10168833 20100708
- International Application: PCT/EP2011/061372 WO 20110706
- International Announcement: WO2012/004287 WO 20120112
- Main IPC: A61K31/4245
- IPC: A61K31/4245 ; C07D271/06
Abstract:
The present invention provides compounds of Formula (I), as selective S1P1 inhibitors, as well as their use for treating multiple sclerosis and other diseases.
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