Invention Grant
US09029544B2 Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
有权
三环吡啶衍生物，含有此类化合物的药物，其用途及其制备方法
- Patent Title: Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation
- Patent Title (中): 三环吡啶衍生物，含有此类化合物的药物，其用途及其制备方法
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Application No.: US13029697Application Date: 2011-02-17
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Publication No.: US09029544B2Publication Date: 2015-05-12
- Inventor: Holger Wagner , Daniela Berta , Klaus Fuchs , Riccardo Giovannini , Dieter Wolfgang Hamprecht , Ingo Konetzki , Ruediger Streicher , Thomas Trieselmann
- Applicant: Holger Wagner , Daniela Berta , Klaus Fuchs , Riccardo Giovannini , Dieter Wolfgang Hamprecht , Ingo Konetzki , Ruediger Streicher , Thomas Trieselmann
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; David L. Kershner; Usha R. Patel
- Priority: EP10154086 20100219
- Main IPC: C07D491/20
- IPC: C07D491/20 ; A61K31/506 ; C07D491/048 ; C07D491/04 ; C07D215/56
Abstract:
The present invention relates to compounds defined by formula I wherein the variables R1-R8 are defined as in the description, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of cholesterol ester transfer protein (CETP) and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme.
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