Invention Grant
- Patent Title: Use of alpha-hydroxy carbonyl compounds as reducing agents
- Patent Title (中): 使用α-羟基羰基化合物作为还原剂
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Application No.: US12159363Application Date: 2006-12-29
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Publication No.: US09029569B2Publication Date: 2015-05-12
- Inventor: Richard J. Knox
- Applicant: Richard J. Knox
- Applicant Address: GB Carmarthen
- Assignee: Morvus Technology Limited
- Current Assignee: Morvus Technology Limited
- Current Assignee Address: GB Carmarthen
- Agency: Morrison & Foerster LLP
- Priority: GB0526552.5 20051229
- International Application: PCT/GB2006/004947 WO 20061229
- International Announcement: WO2007/074344 WO 20070705
- Main IPC: C07D203/14
- IPC: C07D203/14 ; C07B31/00 ; A61K31/04 ; A61K31/045 ; A61K31/12 ; A61K31/396 ; A61K45/06

Abstract:
There is provided the use as reducing agents of alpha-hydroxycarbonyl compounds capable of forming cyclic dimers. There is also provided corresponding methods of reducing reducible compounds, particularly reduction-activated prodrugs. Examples of the alpha-hydroxycarbonyl compounds used are dihydroxyacetone, glycolaldehyde, glyceraldehyde, erythrose, xylulose, erythrulose or 3-hydroxy-2-butanone.
Public/Granted literature
- US20100104515A1 USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS Public/Granted day:2010-04-29
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