Invention Grant
- Patent Title: Method of using a lead to regulate protein expression
- Patent Title (中): 使用铅调节蛋白质表达的方法
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Application No.: US11277552Application Date: 2006-03-27
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Publication No.: US09031792B2Publication Date: 2015-05-12
- Inventor: Darrell O. Wagner , Haris J. Sih , Jihong Qu , Jeffrey Ross , Steven D. Girouard , Ronald W. Heil, Jr.
- Applicant: Darrell O. Wagner , Haris J. Sih , Jihong Qu , Jeffrey Ross , Steven D. Girouard , Ronald W. Heil, Jr.
- Applicant Address: US MN St. Paul
- Assignee: Cardiac Pacemakers, Inc.
- Current Assignee: Cardiac Pacemakers, Inc.
- Current Assignee Address: US MN St. Paul
- Agency: Schwegman Lundberg & Woessner, P.A.
- Main IPC: G01N33/48
- IPC: G01N33/48 ; A61K48/00 ; A61N1/05
Abstract:
A system and device are provided which include a gene regulatory system controlling expression of one or more expression cassettes present in or released by the device, by emitting one or more stimulations. An expression cassette includes a regulatable transcription control element that is responsive to the emitted stimulations linked to an open reading frame of interest. The system optionally includes a sensor to sense a parameter indicative of a need, a telemetry module to receive an external command, or a programmable device, for regulating gene expression of the open reading frame.
Public/Granted literature
- US20070036771A1 BIOLOGIC DEVICE FOR REGULATION OF GENE EXPRESSION AND METHOD THEREFOR Public/Granted day:2007-02-15
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