Invention Grant
US09034303B2 Neuroprotective and neuro-restorative iron chelators and monoamine oxidase inhibitors and uses thereof
有权
神经保护和神经修复铁螯合剂和单胺氧化酶抑制剂及其用途
- Patent Title: Neuroprotective and neuro-restorative iron chelators and monoamine oxidase inhibitors and uses thereof
- Patent Title (中): 神经保护和神经修复铁螯合剂和单胺氧化酶抑制剂及其用途
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Application No.: US13816874Application Date: 2011-08-12
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Publication No.: US09034303B2Publication Date: 2015-05-19
- Inventor: Vincent R. Zurawski, Jr. , David M. Stout , Theodore J. Nitz , Moussa B. H. Youdim , Orly Weinreb
- Applicant: Vincent R. Zurawski, Jr. , David M. Stout , Theodore J. Nitz , Moussa B. H. Youdim , Orly Weinreb
- Agency: Browdy and Neimark, PLLC
- International Application: PCT/IB2011/053590 WO 20110812
- International Announcement: WO2012/020389 WO 20120216
- Main IPC: C07D215/28
- IPC: C07D215/28 ; C07D215/26 ; C07D215/32 ; C07D405/06
Abstract:
8-Hydroxy-quinoline derivatives and 8-ethers, 8-esters, 8-carbonates, 8-acyloxymethyl, 8-phosphates, (phosphoryloxy)methyl, and 8-carbamates derivatives thereof are described that exhibit iron chelation, neuroprotective, neurorestorative, apoptotic and/or selective MAO-AB inhibitory activities.
Public/Granted literature
- US20130330284A1 NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF Public/Granted day:2013-12-12
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