Invention Grant
- Patent Title: Protofibril selective antibodies and the use thereof
- Patent Title (中): 原始纤维选择性抗体及其用途
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Application No.: US13219012Application Date: 2011-08-26
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Publication No.: US09034334B2Publication Date: 2015-05-19
- Inventor: Pär Gellerfors , Lars Lannfelt , Dag Sehlin , Frida Ekholm Pettersson , Hillevi Englund
- Applicant: Pär Gellerfors , Lars Lannfelt , Dag Sehlin , Frida Ekholm Pettersson , Hillevi Englund
- Applicant Address: SE Stockholm
- Assignee: BioArctic Neuroscience AB
- Current Assignee: BioArctic Neuroscience AB
- Current Assignee Address: SE Stockholm
- Agency: Clark & Elbing LLP
- Priority: SE0600662 20060323; SE0602591 20061130
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; G01N33/68 ; C07K16/18 ; C07K16/46
Abstract:
The invention relates to an isolated antibody, or fragment thereof, having high affinity for human Aβ protofibrils. The invention further relates to compositions that include the antibody, or a fragment thereof, and a pharmaceutically acceptable buffer. The invention further relates to a method of preventing or treating Alzheimer's disease, which includes the step of administering to a patient having or suspected of having Alzheimer's disease such an antibody, or fragment thereof or a composition that includes the antibody or a fragment thereof.
Public/Granted literature
- US20120076726A1 PROTOFIBRIL SELECTIVE ANTIBODIES AND THE USE THEREOF Public/Granted day:2012-03-29
Information query
