Invention Grant
US09034337B2 Treatment and delay of outset of synucleinopathic and amyloidogenic disease
有权
突触核蛋白病和淀粉样变性疾病的治疗和延迟开始
- Patent Title: Treatment and delay of outset of synucleinopathic and amyloidogenic disease
- Patent Title (中): 突触核蛋白病和淀粉样变性疾病的治疗和延迟开始
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Application No.: US11710248Application Date: 2007-02-23
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Publication No.: US09034337B2Publication Date: 2015-05-19
- Inventor: Dale B. Schenk , Eliezar Masliah , Manuel J. Buttini , Tamie J. Chilcote , Edward Rockenstein , Kate Dora Games
- Applicant: Dale B. Schenk , Eliezar Masliah , Manuel J. Buttini , Tamie J. Chilcote , Edward Rockenstein , Kate Dora Games
- Applicant Address: IE
- Assignee: Prothena Biosciences Limited
- Current Assignee: Prothena Biosciences Limited
- Current Assignee Address: IE
- Agency: Alston & Bird LLP
- Main IPC: A61K39/385
- IPC: A61K39/385 ; A61K39/05 ; A61K39/08 ; A61K39/39 ; A61K45/00 ; A61K39/00 ; C07K16/18
Abstract:
The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
Public/Granted literature
- US20090208487A1 Prevention and treatment of synucleinopathic and amyloidogenic disease Public/Granted day:2009-08-20
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