Invention Grant
- Patent Title: Chimeric adenoviruses for use in cancer treatment
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Application No.: US13862875Application Date: 2013-04-15
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Publication No.: US09034344B2Publication Date: 2015-05-19
- Inventor: Paul Harden , Terry Hermiston , Irene Kuhn
- Applicant: PsiOxus Therapeutics Limited
- Applicant Address: GB London
- Assignee: PsiOxus Therapeutics Limited
- Current Assignee: PsiOxus Therapeutics Limited
- Current Assignee Address: GB London
- Agency: Banner & Witcoff, Ltd.
- Main IPC: C12N15/861
- IPC: C12N15/861 ; C12N7/00 ; C12N15/86 ; A61K38/45 ; A61K35/00
Abstract:
The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
Public/Granted literature
- US20130217095A1 CHIMERIC ADENOVIRUSES FOR USE IN CANCER TREATMENT Public/Granted day:2013-08-22
Information query
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