Invention Grant
- Patent Title: Intrinsically fluorescent carbon nanospheres and a process thereof
- Patent Title (中): 本征荧光碳纳米球及其工艺
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Application No.: US12681596Application Date: 2008-09-30
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Publication No.: US09034387B2Publication Date: 2015-05-19
- Inventor: Tapas Kumar Kundu , Eswaramoorthy Muthusamy, Sr. , Ruthrotha Selvi Bharatha Vikru , Dinesh Jagadeesan
- Applicant: Tapas Kumar Kundu , Eswaramoorthy Muthusamy, Sr. , Ruthrotha Selvi Bharatha Vikru , Dinesh Jagadeesan
- Applicant Address: IN Karnataka
- Assignee: Jawaharlal Nehru Centre for Advanced Scientific Research
- Current Assignee: Jawaharlal Nehru Centre for Advanced Scientific Research
- Current Assignee Address: IN Karnataka
- Agency: Fenwick & West LLP
- Priority: IN2218/CHE/2007 20071003
- International Application: PCT/IN2008/000632 WO 20080930
- International Announcement: WO2009/044410 WO 20090409
- Main IPC: A61K9/51
- IPC: A61K9/51 ; A61K47/36 ; A61K9/14 ; C12N5/02 ; C07C235/64 ; A61K31/235 ; A61K47/00 ; A61P3/10 ; A61P11/06 ; A61P35/00 ; A61P31/18
Abstract:
The present invention provides solution to the problem involved in delivery of active molecules to nucleus. More particularly, the invention provides intrinsically fluorescent and inherently surface functionalized carbon nanospheres which are non-toxic. Also, these carbon nanospheres [CSP] were adsorbed with CTPB [CSP-CTPB] and the adsorbed CSP-CTPB are permeable to cells with nuclear targeting ability. In addition, the present invention provides a composition, a process to prepare the composition comprising CSP with adsorbed active/therapeutic molecules. Further, the instant invention provides a method for delivering active molecules inside a cell nucleus.
Public/Granted literature
- US20100215760A1 INTRINSCIALLY FLUORESCENT CARBON NANOSPHERES AND A PROCESS THEREOF Public/Granted day:2010-08-26
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