Invention Grant
- Patent Title: Tricyclic compounds and methods of use therefor
- Patent Title (中): 三环化合物及其使用方法
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Application No.: US13768873Application Date: 2013-02-15
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Publication No.: US09034866B2Publication Date: 2015-05-19
- Inventor: Steven Staben , Georgette Castanedo , Christian A. G. N. Montalbetti , Jianwen Feng
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Genentech, Inc.
- Agent Tamara Kale
- Main IPC: C07D498/04
- IPC: C07D498/04 ; C07D498/14 ; C07D519/00 ; C07D513/04 ; C07D498/00 ; C07D498/12
Abstract:
The invention relates to novel compounds of Formula I: wherein A1, A2, A3, A4, A5, A6, R2, R4, R5, R6, R7, R8 and subscripts m and n each has the meaning as described herein. Compounds of Formula I and pharmaceutical compositions thereof are useful in the treatment of disease and disorders in which undesired or over-activation of NF-kB signaling is observed.
Public/Granted literature
- US20130217666A1 TRICYCLIC COMPOUNDS AND METHODS OF USE THEREFOR Public/Granted day:2013-08-22
Information query
