Invention Grant
- Patent Title: Bromodomain inhibitors
- Patent Title (中): 溴代抑制剂
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Application No.: US14517705Application Date: 2014-10-17
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Publication No.: US09034900B2Publication Date: 2015-05-19
- Inventor: Michael John Bennett , Juan Manuel Betancort , Amogh Boloor , Stephen W. Kaldor , Jeffrey Alan Stafford , James Marvin Veal
- Applicant: Quanticel Pharmaceuticals
- Applicant Address: US CA San Diego
- Assignee: Quanticel Pharmaceuticals, Inc.
- Current Assignee: Quanticel Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K31/47
- IPC: A61K31/47 ; C07D217/24 ; C07D498/04 ; C07D413/04 ; C07D401/04 ; C07D471/04 ; C07D405/04 ; C07D487/04 ; C07D211/94
Abstract:
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.
Public/Granted literature
- US20150111885A1 BROMODOMAIN INHIBITORS Public/Granted day:2015-04-23
Information query
