Invention Grant
- Patent Title: Bombesin analog peptide antagonist conjugates
- Patent Title (中): 熊果苷类似物拮抗剂共轭物
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Application No.: US12921209Application Date: 2009-02-27
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Publication No.: US09035023B2Publication Date: 2015-05-19
- Inventor: Helmut Maecke , Jean Claude Reubi , Rosalba Mansi
- Applicant: Helmut Maecke , Jean Claude Reubi , Rosalba Mansi
- Applicant Address: CH Matran
- Assignee: Piramal Imaging, SA
- Current Assignee: Piramal Imaging, SA
- Current Assignee Address: CH Matran
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: EP08075180 20080307
- International Application: PCT/EP2009/001403 WO 20090227
- International Announcement: WO2009/109332 WO 20090911
- Main IPC: A61K51/08
- IPC: A61K51/08 ; C07K7/06 ; C07K7/08
Abstract:
To provide a diagnostic and therapeutic medicament, a bombesin analog peptide antagonist conjugate is provided which has general Formula (I), wherein A is a metal chelator comprising at least one radionuclide metal, B is a spacer linked to N-terminal of C or a covalent bond and C is a bombesin analog peptide antagonist having a sequence as claimed, where further x is an integer from 1 to 3 and n is an integer from 1 to 6. [A-(B)n]x—C (I)
Public/Granted literature
- US20110097266A1 Bombesin Analog Peptide Antagonist Conjugates Public/Granted day:2011-04-28
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