A pneumatic tire unit comprises a front tire to be mounted on a leading side of a vehicle, and a rear tire to be mounted on a trailing side of the vehicle. A plurality of recesses is provided in at least one tire side portion of the front tire, and a plurality of protrusions is provided on at least one tire side portion of the rear tire. A negative pressure region that can be generated at a back surface side of the vehicle is reduced and, therefore, air resistance of the vehicle is reduced and fuel economy is enhanced.