Invention Grant
US09040496B2 Reduction of ALMS1 gene expression or inhibition of altröm protein to induce cardiomyocyte proliferation
有权
减少ALMS1基因表达或抑制altrö蛋白诱导心肌细胞增殖
- Patent Title: Reduction of ALMS1 gene expression or inhibition of altröm protein to induce cardiomyocyte proliferation
- Patent Title (中): 减少ALMS1基因表达或抑制altrö蛋白诱导心肌细胞增殖
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Application No.: US14089833Application Date: 2013-11-26
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Publication No.: US09040496B2Publication Date: 2015-05-26
- Inventor: Daniel Philip Judge , Peter Andersen , Lincoln Takura Shenje
- Applicant: THE JOHNS HOPKINS UNIVERSITY
- Applicant Address: US MD Baltimore
- Assignee: The Johns Hopkins University
- Current Assignee: The Johns Hopkins University
- Current Assignee Address: US MD Baltimore
- Agency: Johns Hopkins Technology Transfer
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C07H21/04 ; C12N15/11 ; C12N15/113

Abstract:
The present invention relates to the field of cardiology. More specifically, the present invention provides methods and compositions for inducing proliferation of cardiomyocytes. In a specific embodiment, a method for inducing proliferation of cardiomyocytes comprises the step of administering an effective amount of an ALMS1 inhibitor.
Public/Granted literature
- US20140179763A1 REDUCTION OF ALMS1 GENE EXPRESSION OR INHIBITION OF ALTROM PROTEIN TO INDUCE CARDIOMYOCYTE PROLIFERATION Public/Granted day:2014-06-26
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