Invention Grant
- Patent Title: 1H-benzimidazole-5-carboxamides as anti-inflammatory agents
- Patent Title (中): 1H-苯并咪唑-5-甲酰胺作为抗炎剂
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Application No.: US13119835Application Date: 2009-09-25
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Publication No.: US09040565B2Publication Date: 2015-05-26
- Inventor: Roland Pfau , Kirsten Arndt , Henri Doods , Norbert Hauel , Klaus Klinder , Raimund Kuelzer , Juergen Mack , Dirk Stenkamp
- Applicant: Roland Pfau , Kirsten Arndt , Henri Doods , Norbert Hauel , Klaus Klinder , Raimund Kuelzer , Juergen Mack , Dirk Stenkamp
- Applicant Address: SE Uppsala
- Assignee: Orexo AB
- Current Assignee: Orexo AB
- Current Assignee Address: SE Uppsala
- Agency: K&L Gates LLP
- Agent Louis C. Cullman; Michelle Glasky Bergman
- Priority: EP08165120 20080925
- International Application: PCT/EP2009/062422 WO 20090925
- International Announcement: WO2010/034797 WO 20100401
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D401/00 ; C07D221/02 ; C07D471/02 ; C07D235/30 ; C07D263/58 ; C07D277/82 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D405/12 ; C07D413/12 ; C07D417/12 ; C07D471/04

Abstract:
There are provided compounds of formula (I), wherein R1, R6, R8, Q2, Q3, Q3a, Q4, L and A have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation and/or cancer.
Public/Granted literature
- US20120122930A1 1H-Benzimidazole-5-Carboxamides As Anti-Inflammatory Agents Public/Granted day:2012-05-17
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