Invention Grant
- Patent Title: Fluorescent dyes with large stokes shifts
- Patent Title (中): 荧光染料具有较大的斯托克斯位移
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Application No.: US14238640Application Date: 2012-08-10
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Publication No.: US09040704B2Publication Date: 2015-05-26
- Inventor: Warren Edward Piers , Juan Felipe Araneda
- Applicant: Warren Edward Piers , Juan Felipe Araneda
- Applicant Address: CA Calgary, Alberta
- Assignee: UTI LIMITED PARTNERSHIP
- Current Assignee: UTI LIMITED PARTNERSHIP
- Current Assignee Address: CA Calgary, Alberta
- Agency: Hill & Schumacher
- Agent Lynn C. Schumacher; Stephen W. Leonard
- International Application: PCT/CA2012/050544 WO 20120810
- International Announcement: WO2013/023292 WO 20130221
- Main IPC: C09B23/16
- IPC: C09B23/16 ; C09K11/06 ; G01N33/58

Abstract:
Herein are disclosed fluorescent dyes based around a framework for a ligand comprising a pyridyl group linked to a diaryl anilido unit. A variety of ligands based on this framework are disclosed. The ligands chelate to a BF2 center to produce the fluorescent dye. The disclosed dyes combine longer Stokes shifts (approximately 100 nm) with increased quantum yields. They are also photostable in aqueous and organic solutions for several hours. These dyes may be used in the labeling of biomolecules for bioimaging and assays. Also disclosed are methods for the synthesis of these dyes.
Public/Granted literature
- US20140206870A1 FLUORSCENT DYES WITH LARGE STOKES SHIFTS Public/Granted day:2014-07-24
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