Invention Grant
- Patent Title: Pyrrolidine inhibitors of IAP
- Patent Title (中): IAP吡咯烷抑制剂
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Application No.: US14088110Application Date: 2013-11-22
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Publication No.: US09040706B2Publication Date: 2015-05-26
- Inventor: Frederick Cohen , Vickie Hsiao-Wei Tsui , Cuong Ly , John A. Flygare
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: GENENTECH, INC.
- Current Assignee: GENENTECH, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Morrison & Foerster LLP
- Main IPC: C07D277/20
- IPC: C07D277/20 ; C07D453/02 ; C07D471/14 ; C07D471/04 ; C07D417/04 ; C07D417/14

Abstract:
The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, Q, X1, X2, Y, R1, R2, R3, R4, R4′, R5, R6 and R6′ are as described herein.
Public/Granted literature
- US20140080805A1 PYRROLIDINE INHIBITORS OF IAP Public/Granted day:2014-03-20
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