A multi-touch mouse includes a mouse body, a touch pad, and a controlling unit. In a case that the touch pad is not touched and the touch state is OFF, the multi-touch mouse is in a conventional two-dimensional mouse mode. In a case that the touch state of the touch pad is ON in response to a touch action and the mouse body is moved, the controlling unit switches the control mode of the multi-touch mouse to a touch gesture control mode and generates a touch gesture command.