Invention Grant
US09044406B2 Aqueous composition for enteric hard capsule, method of preparing enteric hard capsule, and enteric hard capsule prepared using the method 有权
用于肠溶硬胶囊的水性组合物,制备肠溶性硬胶囊的方法和使用该方法制备的肠溶性硬胶囊

Aqueous composition for enteric hard capsule, method of preparing enteric hard capsule, and enteric hard capsule prepared using the method
Abstract:
An aqueous composition for an enteric hard capsule, a method of preparing an enteric hard capsule, and an enteric hard capsule prepared using the method. The aqueous composition for an enteric hard capsule includes an enteric base material, a capsule forming aid, and a neutralizing agent. The method of preparing an enteric hard capsule includes: preparing an aqueous composition by dissolving an enteric base material, a capsule forming aid, and a neutralizing agent in water; preheating the aqueous composition to a temperature that is less than the gelation temperature for the aqueous composition; immersing a mold pin heated to a temperature that is greater than the gelation temperature for the aqueous composition into the aqueous composition; taking the mold pin out of the aqueous composition to obtain a film formed on the mold pin; and maintaining the film at a temperature that is equal to or greater than the gelation temperature for the aqueous composition for a predetermined period of time to fix the film on the mold pin and drying the film.
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