Invention Grant
US09044437B2 Method for treating alzheimer's disease using pharmacological chaperones to increase the activity of gangliosidases
有权
使用药理学分子伴侣来治疗阿尔茨海默氏病以增加神经节苷脂酶的活性的方法
- Patent Title: Method for treating alzheimer's disease using pharmacological chaperones to increase the activity of gangliosidases
- Patent Title (中): 使用药理学分子伴侣来治疗阿尔茨海默氏病以增加神经节苷脂酶的活性的方法
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Application No.: US13501586Application Date: 2010-10-12
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Publication No.: US09044437B2Publication Date: 2015-06-02
- Inventor: Brandon Wustman , Kenneth Valenzano , Robert Boyd
- Applicant: Brandon Wustman , Kenneth Valenzano , Robert Boyd
- Applicant Address: US NJ Cranbury
- Assignee: Amicus Therapeutics, Inc.
- Current Assignee: Amicus Therapeutics, Inc.
- Current Assignee Address: US NJ Cranbury
- Agency: Servilla Whitney LLC
- International Application: PCT/US2010/052351 WO 20101012
- International Announcement: WO2011/049787 WO 20110428
- Main IPC: A61K31/45
- IPC: A61K31/45 ; A61K38/17
Abstract:
The present invention relates to a method for treating an individual having Alzheimer's Disease by using pharmacological chaperones to increase the activity of gangliosidase and/or sialidase enzymes involved in ganglioside catabolism.
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