Invention Grant
- Patent Title: Biphenyl derivatives useful as glucagon receptor antagonists
- Patent Title (中): 可用作胰高血糖素受体拮抗剂的联苯衍生物
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Application No.: US13478568Application Date: 2012-05-23
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Publication No.: US09045389B2Publication Date: 2015-06-02
- Inventor: Devraj Chakravarty , Michael Greco , Brian Shook , Guozhang Xu , Rui Zhang
- Applicant: Devraj Chakravarty , Michael Greco , Brian Shook , Guozhang Xu , Rui Zhang
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agent Jeremy K. McKown
- Main IPC: A61K31/166
- IPC: A61K31/166 ; C07C229/52 ; C07C237/36
Abstract:
The present invention is directed to biphenyl derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic diseases such as Type II diabetes mellitus and obesity.
Public/Granted literature
- US20120302641A1 BIPHENYL DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS Public/Granted day:2012-11-29
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