Invention Grant
- Patent Title: Targeting of EWS-FLI1 as anti-tumor therapy
- Patent Title (中): 靶向EWS-FLI1作为抗肿瘤治疗
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Application No.: US12720616Application Date: 2010-03-09
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Publication No.: US09045415B2Publication Date: 2015-06-02
- Inventor: Jeffrey A. Toretsky , Aykut Üren , Milton Lang Brown , Yali Kong
- Applicant: Jeffrey A. Toretsky , Aykut Üren , Milton Lang Brown , Yali Kong
- Applicant Address: US DC Washington
- Assignee: Georgetown University
- Current Assignee: Georgetown University
- Current Assignee Address: US DC Washington
- Agency: Knobbe, Martens, Olson & Bear LLP
- Main IPC: C07D401/06
- IPC: C07D401/06 ; C07D209/38 ; A61K38/00 ; C07K7/06 ; C07K7/08
Abstract:
Peptides and compounds are provided that function as EWS-FLI1 protein inhibitors. The peptides and compounds have utility in the treatment of Ewing's sarcoma family of tumors. Also provided are methods of preparing the compounds and assays for identifying inhibitors of EWS-FLI1 protein.
Public/Granted literature
- US20100167994A1 TARGETING OF EWS-FLI1 AS ANTI-TUMOR THERAPY Public/Granted day:2010-07-01
Information query
