Invention Grant
- Patent Title: Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
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Application No.: US14081940Application Date: 2013-11-15
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Publication No.: US09045420B2Publication Date: 2015-06-02
- Inventor: George A. Doherty , Steven W. Elmore , Lisa Hasvold , Laura A. Hexamer , Robert A. Mantei , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao , Gary T. Wang , Le Wang , Xilu Wang , Michael D. Wendt , Todd M. Hansen
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: ABBVIE INC.
- Current Assignee: ABBVIE INC.
- Current Assignee Address: US IL North Chicago
- Agency: Jones Day
- Main IPC: A61K31/416
- IPC: A61K31/416 ; C07D403/14 ; C07D413/14 ; C07D215/14 ; C07D209/32 ; C07D211/96 ; C07D213/64 ; C07D215/20 ; C07D217/16 ; C07D231/56 ; C07D235/26 ; C07D249/04 ; C07D295/125 ; C07D295/14 ; C07D309/14 ; C07D401/12 ; C07D405/12 ; C07D417/12 ; A61K31/496 ; A61K31/5377 ; A61K45/06 ; C07D295/13 ; C07D309/08 ; C07D487/04 ; C07D209/20 ; C07D295/155 ; C07D309/32
Abstract:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti-apoptotic Bcl-2 protein.
Public/Granted literature
- US20140107119A1 BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES Public/Granted day:2014-04-17
Information query
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