Method for preparation of medetomidine

Invention Grant

US09045433B2 Method for preparation of medetomidine 有权

Title translation: 美托咪定的制备方法

Patent Title: Method for preparation of medetomidine
Patent Title (中): 美托咪定的制备方法
Application No.: US14386054

Application Date: 2012-11-15
Publication No.: US09045433B2

Publication Date: 2015-06-02
Inventor: Florencio Zaragoza Doerwald , Anna Kulesza , Stephan Elzner , Robert Bujok , Zbigniew Wrobel , Krzysztof Wojciechowski
Applicant: LONZA LTD
Applicant Address: CH Visp
Assignee: Lonza Ltd.
Current Assignee: Lonza Ltd.
Current Assignee Address: CH Visp
Agency: Dority & Manning, P.A.
Priority: EP12167134 20120508; WOPCT/EP2012/070870 20121022; EP12192612 20121114
International Application: PCT/EP2012/072796 WO 20121115
International Announcement: WO2013/011155 WO 20130124
Main IPC: C07D233/58
IPC: C07D233/58

Abstract:

The invention discloses a method for the preparation of medetomidine starting from 1-bromo 2,3-dimethylbenzene and aceton.

Abstract(Chinese):

本发明公开了一种从1-溴2,3-二甲苯和丙酮制备中美托咪的方法。

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