Invention Grant
US09045440B2 Desazadesferrothiocin and desazadesferrothiocin polyether analogues as metal chelation agents
有权
脱氮铁硫蛋白和脱氮铁硫蛋白聚醚类似物作为金属螯合剂
- Patent Title: Desazadesferrothiocin and desazadesferrothiocin polyether analogues as metal chelation agents
- Patent Title (中): 脱氮铁硫蛋白和脱氮铁硫蛋白聚醚类似物作为金属螯合剂
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Application No.: US13100705Application Date: 2011-05-04
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Publication No.: US09045440B2Publication Date: 2015-06-02
- Inventor: James Malecha
- Applicant: James Malecha
- Applicant Address: US PA Wayne
- Assignee: FerroKin Biosciences, Inc.
- Current Assignee: FerroKin Biosciences, Inc.
- Current Assignee Address: US PA Wayne
- Agency: Choate, Hall & Stewart, LLP
- Agent Fangli Chen; John P. Rearick
- Main IPC: C07D231/14
- IPC: C07D231/14 ; C07D233/28 ; C07D263/16 ; C07D277/12 ; C07D277/56 ; A61K31/5377 ; A61K31/421 ; A61K31/4172 ; A61K31/426 ; A61K31/496
Abstract:
Disclosed herein are new compounds of desazadesferrothiocin polyether (DADFT-PE) analogs, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
Public/Granted literature
- US20110275636A1 DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS Public/Granted day:2011-11-10
Information query
