Invention Grant
- Patent Title: Molecules and methods for modulating TMEM16A activities
- Patent Title (中): 分子和调节TMEM16A活性的方法
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Application No.: US13690269Application Date: 2012-11-30
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Publication No.: US09045546B2Publication Date: 2015-06-02
- Inventor: Larry Alexander Gaither , Christopher John Rothwell
- Applicant: Larry Alexander Gaither , Christopher John Rothwell
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/30
Abstract:
The present invention provides molecules that bind to TMEM16A (“TMEM16A binding molecules”), particularly human or humanized antibodies and antibody drug conjugates that bind to human TMEM16A and modulate its functions. Epitopes of TMEM16A and molecules that bind these epitopes are also provided herein.
Public/Granted literature
- US20130323252A1 Molecules And Methods For Modulating TMEM16A Activities Public/Granted day:2013-12-05
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