Invention Grant
- Patent Title: Double stranded RNA compounds to RhoA and use thereof
- Patent Title (中): RhoA的双链RNA化合物及其用途
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Application No.: US13700942Application Date: 2011-06-23
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Publication No.: US09045755B2Publication Date: 2015-06-02
- Inventor: Sharon Avkin-Nachum , Elena Feinstein , Hagar Kalinski , Igor Mett
- Applicant: Sharon Avkin-Nachum , Elena Feinstein , Hagar Kalinski , Igor Mett
- Applicant Address: US CA Fremont
- Assignee: QUARK PHARMACEUTICALS, INC.
- Current Assignee: QUARK PHARMACEUTICALS, INC.
- Current Assignee Address: US CA Fremont
- Agency: Cooper & Dunham LLP
- Agent John P. White
- International Application: PCT/US2011/041562 WO 20110623
- International Announcement: WO2011/163436 WO 20111229
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/113
Abstract:
The present invention relates to compounds, pharmaceutical compositions comprising same, methods of use thereof and kits for the down-regulation of RhoA gene. The compounds, compositions, methods and kits are useful in the treatment of subjects suffering from diseases or conditions and or symptoms associated with diseases or conditions in which RhoA expression has adverse consequences and for conferring neuroprotection.
Public/Granted literature
- US20130137750A1 DOUBLE STRANDED RNA COMPOUNDS TO RHOA AND USE THEREOF Public/Granted day:2013-05-30
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