Invention Grant
US09045793B2 Method of regulating the expression level of survival of motor neuron 1
有权
调节运动神经元存活表达水平的方法1
- Patent Title: Method of regulating the expression level of survival of motor neuron 1
- Patent Title (中): 调节运动神经元存活表达水平的方法1
-
Application No.: US13032846Application Date: 2011-02-23
-
Publication No.: US09045793B2Publication Date: 2015-06-02
- Inventor: Yuh-Jyh Jong , Shih-Hsien Hsu , Jan-Gowth Chang
- Applicant: Yuh-Jyh Jong , Shih-Hsien Hsu , Jan-Gowth Chang
- Applicant Address: TW Kaohsiung
- Assignee: KAOHSIUNG MEDICAL UNIVERSITY
- Current Assignee: KAOHSIUNG MEDICAL UNIVERSITY
- Current Assignee Address: TW Kaohsiung
- Agency: WPAT, P.C.
- Agent Anthony King
- Main IPC: A61K31/404
- IPC: A61K31/404 ; C12Q1/37 ; A61K31/7105 ; G01N33/50 ; G01N33/68
Abstract:
The present invention relates to a method of regulating the expression level of survival of motor neuron 1 (SMN1) comprising administering to a subject in need thereof a therapeutically effective amount of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) regulator and a pharmaceutically acceptable carrier. The present invention also relates to a method of detecting enzyme activity of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) in human fibroblasts comprising detecting protein expression level of survival of motor neuron 1 (SMN1).
Public/Granted literature
Information query
IPC分类:
