Invention Grant
US09046537B2 Method for treating inflammation by administering a compound which binds LDL-receptor-related protein (LRP) ligand binding domain
有权
通过施用结合LDL-受体相关蛋白（LRP）配体结合结构域的化合物来治疗炎症的方法
- Patent Title: Method for treating inflammation by administering a compound which binds LDL-receptor-related protein (LRP) ligand binding domain
- Patent Title (中): 通过施用结合LDL-受体相关蛋白（LRP）配体结合结构域的化合物来治疗炎症的方法
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Application No.: US12221863Application Date: 2008-08-07
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Publication No.: US09046537B2Publication Date: 2015-06-02
- Inventor: Elazar Rabbani , Xiaofeng Li , Dakai Liu , Yazhou Zhang , Richard Jin , Riddhi Bhattacharyya , Wei Cheng , James J. Donegan
- Applicant: Elazar Rabbani , Xiaofeng Li , Dakai Liu , Yazhou Zhang , Richard Jin , Riddhi Bhattacharyya , Wei Cheng , James J. Donegan
- Applicant Address: US NY New York
- Assignee: Enzo Biochem, Inc.
- Current Assignee: Enzo Biochem, Inc.
- Current Assignee Address: US NY New York
- Agent Anna DiGabriele Petti
- Main IPC: A01N43/00
- IPC: A01N43/00 ; A61K31/33 ; A01N61/00 ; A61K31/00 ; A61K31/535 ; A01N43/02 ; A61K31/335 ; A01N43/16 ; A61K31/35 ; G01N33/92 ; A61K31/015 ; A61K31/395 ; G01N33/50 ; G01N33/564 ; A61K38/00
Abstract:
The present invention relates to the field of therapeutic methods, compositions and uses thereof, that affect, directly or indirectly, the behavior of LRP receptors. These compositions and methods result in the treatment of inflammatory, immunological and metabolic conditions. More particularly, the methods and compositions of the invention are directed to the identification of small molecules, drugs and/or pharmacological agents that affect the Wnt pathway by affecting normal complex formation among various signaling receptors, the LRP5 and LRP6 receptor, and related ligands.
Public/Granted literature
- US20120184616A9 Methods for treating inflammation Public/Granted day:2012-07-19
Information query
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