Invention Grant
- Patent Title: Oral dosage form, comprising at least one biologically active agent, formulation auxiliary substances and magnetizable particles
- Patent Title (中): 口服剂型,包含至少一种生物活性剂,制剂辅助物质和可磁化颗粒
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Application No.: US13390353Application Date: 2010-08-30
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Publication No.: US09050256B2Publication Date: 2015-06-09
- Inventor: Benedikt Hartwig , Norbert Windhab , Melanie Liefke , Juan Tome Alcalde , Michael Damm , Rosario Lizio , Michael Gottschalk , Angela Olf , Christian Meier , Andreas Gryczke
- Applicant: Benedikt Hartwig , Norbert Windhab , Melanie Liefke , Juan Tome Alcalde , Michael Damm , Rosario Lizio , Michael Gottschalk , Angela Olf , Christian Meier , Andreas Gryczke
- Applicant Address: DE Darmstadt
- Assignee: Evonik Röhm Gmbh
- Current Assignee: Evonik Röhm Gmbh
- Current Assignee Address: DE Darmstadt
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: DE102009029170 20090903
- International Application: PCT/EP2010/062641 WO 20100830
- International Announcement: WO2011/026808 WO 20110310
- Main IPC: A61B5/055
- IPC: A61B5/055 ; A61K9/20 ; A61K9/28 ; A61K9/48 ; A61K9/50 ; A61K9/00

Abstract:
The invention relates to an oral dosage form, comprising at least one biologically active agent, formulation auxiliary substances and magnetizable particles, wherein the dosage form has an at least two phase composition, wherein the phases can dissolve in the body after oral administration due to their formulation and the magnetizable particles are bound in formulation auxiliary substances and are present in a magnetized state, wherein the magnetized particles are present in at least two phases of the dosage form and generate magnetic fields, wherein these phases dissolve at different times in the body after oral administration, and wherein the magnetic field strength with respect to time, position and movement in the body is acquired using a detection system and can be evaluated using a computer-based evaluation system.
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