Invention Grant
- Patent Title: Conjugate based systems for controlled drug delivery
- Patent Title (中): 用于控制药物递送的基于共轭体系
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Application No.: US13145532Application Date: 2010-01-27
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Publication No.: US09050370B2Publication Date: 2015-06-09
- Inventor: Todd C. Zion , Thomas M. Lancaster
- Applicant: Todd C. Zion , Thomas M. Lancaster
- Applicant Address: US MA Beverly
- Assignee: SMARTCELLS, INC.
- Current Assignee: SMARTCELLS, INC.
- Current Assignee Address: US MA Beverly
- Agent Immac J. Thampoe; John David Reilly
- International Application: PCT/US2010/022268 WO 20100127
- International Announcement: WO2010/088294 WO 20100805
- Main IPC: A61K38/28
- IPC: A61K38/28 ; A01N43/04 ; A61K31/70 ; A61K47/48
Abstract:
Conjugates which comprise a drug and a ligand which includes a first saccharide; wherein the conjugate is characterized in that, when the conjugate is administered to a mammal, at least one pharmacokinetic or pharmacodynamic property of the conjugate is sensitive to serum concentration of a second saccharide. Exemplary conjugates and sustained release formulations are provided in addition to methods of use and preparation.
Public/Granted literature
- US20110301083A1 CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY Public/Granted day:2011-12-08
Information query
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