Invention Grant
US09050444B2 Drug delivery and substance transfer facilitated by nano-enhanced device having aligned carbon nanotubes protruding from device surface
有权
由具有从器件表面突出的对准的碳纳米管的纳米增强器件促进药物递送和物质转移
- Patent Title: Drug delivery and substance transfer facilitated by nano-enhanced device having aligned carbon nanotubes protruding from device surface
- Patent Title (中): 由具有从器件表面突出的对准的碳纳米管的纳米增强器件促进药物递送和物质转移
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Application No.: US13762197Application Date: 2013-02-07
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Publication No.: US09050444B2Publication Date: 2015-06-09
- Inventor: Morteza Gharib , Adrianus I. Aria , Elijah Bodhi Sansom
- Applicant: California Institute of Technology
- Applicant Address: US CA Pasadena
- Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
- Current Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
- Current Assignee Address: US CA Pasadena
- Agency: One LLP
- Main IPC: A61M5/00
- IPC: A61M5/00 ; A61M37/00 ; A61K47/48 ; A61L27/44 ; A61L27/54 ; A61L27/56 ; B29C70/64 ; B82Y5/00 ; B82Y30/00 ; B82Y40/00 ; C01B31/02 ; A61B5/145 ; A61M5/44 ; A61M25/10 ; A61N1/30 ; A61N5/06 ; B29K105/16
Abstract:
The present invention relates to a nano-enhanced device for substance transfer between the device and a tissue. The device comprises a substrate with substantially aligned carbon nanotubes anchored within the substrate, and with at least one end of the carbon nanotubes protruding from the substrate. The protruding nanotube ends may be coated with a drug for delivery of the drug into body tissue. The present invention may be incorporated into an angioplasty catheter balloon or into a patch that is worn on the skin. The carbon nanotubes can be grouped in clusters to effectively form nano-needles which can transfer fluid to or from the subdermal tissue. The nano-needles can be used in conjunction with a sensor to ascertain body fluid information such as pH, glucose level, etc.
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