A ball pitching machine includes a tripod, a mounting base, two rotary wheel devices, and a ball holder. The mounting base includes an engaging member rotatably mounted to a pillar of the tripod and a mounting plate pivotably coupled to the engaging member. The rotary wheel devices are mounted on two sides of the mounting plate and each includes a rotary wheel. The ball holder is mounted to the mounting plate and located between the rotary wheel devices. The ball holder of the ball pitching machine is applicable to different-sized rugby balls or soccer balls and can be easily adjusted to any elevation angle. The ball pitching machine allows elevation angles of the mounting base to be adjusted, and also allows elevation angles of the rotary wheels to be adjusted.