Invention Grant
US09051248B2 Methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid
有权
用于递送1,3-丙二磺酸的方法,化合物和组合物
- Patent Title: Methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid
- Patent Title (中): 用于递送1,3-丙二磺酸的方法,化合物和组合物
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Application No.: US13389606Application Date: 2010-08-06
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Publication No.: US09051248B2Publication Date: 2015-06-09
- Inventor: Xianqi Kong , Nigel Levens , Abderrahim Bouzide , Stephane Ciblat , Richard Frenette , Johanne Renaud
- Applicant: Xianqi Kong , Nigel Levens , Abderrahim Bouzide , Stephane Ciblat , Richard Frenette , Johanne Renaud
- Applicant Address: CA Laval
- Assignee: BHI Limited Partnership
- Current Assignee: BHI Limited Partnership
- Current Assignee Address: CA Laval
- Agency: McCarter & English, LLP
- Agent Danielle L. Herritt; Emily Dertz
- International Application: PCT/CA2010/001229 WO 20100806
- International Announcement: WO2011/017800 WO 20110217
- Main IPC: C07C309/65
- IPC: C07C309/65 ; C07D319/06 ; A61K31/366 ; A61K31/365 ; A61K31/255 ; C07D309/22 ; A61K31/351 ; C07C309/05 ; C07C311/06 ; C07C311/51 ; C07D213/64 ; C07D213/65 ; C07D231/12 ; C07D307/33 ; C07D307/58 ; C07D307/77 ; C07D327/10 ; C07F9/09 ; C07F9/40

Abstract:
The invention relates to methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid (1,3PDS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 1,3PDS, either in vitro or in vivo. The invention also relates to sulfonate ester prodrugs of 1,3PDS as well as Gemini dimmers and oligomers of 1,3PDS for the prevention or treatment of associated diseases and conditions.
Public/Granted literature
- US20120208850A1 METHODS, COMPOUNDS, AND COMPOSITIONS FOR DELIVERING 1,3-PROPANEDISULFONIC ACID Public/Granted day:2012-08-16
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