Invention Grant
US09051253B2 Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's
有权
用于治疗淀粉样蛋白病和突触核蛋白病如阿尔茨海默病，2型糖尿病和帕金森病的化合物，组合物和方法
- Patent Title: Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's
- Patent Title (中): 用于治疗淀粉样蛋白病和突触核蛋白病如阿尔茨海默病，2型糖尿病和帕金森病的化合物，组合物和方法
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Application No.: US13887762Application Date: 2013-05-06
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Publication No.: US09051253B2Publication Date: 2015-06-09
- Inventor: Alan D. Snow , Beth Nguyen , Gerardo Castillo , Virginia Sanders , Thomas Lake , Lesley Larsen
- Applicant: Alan D. Snow , Beth Nguyen , Gerardo Castillo , Virginia Sanders , Thomas Lake , Lesley Larsen
- Applicant Address: US WA Kirkland
- Assignee: PROTEOTECH INC.
- Current Assignee: PROTEOTECH INC.
- Current Assignee Address: US WA Kirkland
- Agent Rebecca Eagen
- Main IPC: A61K31/047
- IPC: A61K31/047 ; A61K31/05 ; C07C49/248 ; C07C39/15 ; C07C39/16 ; C07C39/17 ; C07C45/62 ; C07C45/64 ; C07C49/83 ; C07C49/835 ; C07C69/017 ; C07C215/50 ; C07C231/02 ; C07C235/34 ; C07C235/38 ; C07C235/48 ; C07C235/54 ; C07C235/56 ; C07C237/22 ; C07C275/34 ; C07D207/16 ; C07D211/74 ; C07D213/30 ; C07D213/69 ; C07D213/85 ; C07D221/08 ; C07D221/18 ; C07D231/06 ; C07D241/08 ; C07D263/38 ; C07D265/38 ; C07D295/096 ; C07D295/192 ; C07D311/60 ; C07D317/50 ; C07D317/54 ; C07D317/58 ; C07D317/60 ; C07D317/66 ; C07D317/68 ; C07D333/16 ; C07D405/14 ; C07D407/14 ; C07D409/14 ; C07D413/14 ; C07D451/06 ; C07D471/04 ; C07D487/08 ; C07D491/08
Abstract:
The use of 3,4,3′,4′-tetrahydroxychalcone in the treatment of amyloid diseases, especially Aβ amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease.
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