Invention Grant
- Patent Title: Substituted pyridine derivatives useful in the treatment of cancer
- Patent Title (中): 用于治疗癌症的取代吡啶衍生物
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Application No.: US14074973Application Date: 2013-11-08
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Publication No.: US09051271B2Publication Date: 2015-06-09
- Inventor: Ibrahim Mahmoud Abdou , Alaa ElDin Abdel Aziz Salem , Abdu Adem , Hussein F. Zhodi , Hany Abdel Aziz El Deab
- Applicant: United Arab Emirates University
- Applicant Address: AE
- Assignee: UNITED ARAB EMIRATES UNIVERSITY
- Current Assignee: UNITED ARAB EMIRATES UNIVERSITY
- Current Assignee Address: AE
- Agency: Katten Muchin Rosenman LLP
- Priority: GB1220144.8 20121108
- Main IPC: A61K31/655
- IPC: A61K31/655 ; C07D213/85 ; A61K45/06

Abstract:
The present invention describes compounds of formula (I) Wherein: R1 is selected from C1-C6 alkyl, CF3, Phenyl & 2-thienyl R2 is selected from C1-C6 alkyl, phenyl & CF3 R3 is selected from H, C1-C6 alkyl, halo, NO2, NH2, haloalkyl R4 is selected from H, C1-C6 alkyl, halo, NO2, NH2, haloalkyl R5 is selected from H, C1-C6 alkyl, halo, NO2, NH2, haloalkyl R6 is selected from H, —(CH2)nC(O)OR7 & C(O)C6H4—R7 R7 is selected from C1-C6 alkyl, phenyl optionally substituted by 1-3 substituents selected from CF3, NO2 and halo. n is 0-6 These compounds have been identified as novel anticancer agents.
Public/Granted literature
- US20140128350A1 Substituted Pyridine Derivatives Useful In The Treatment Of Cancer Public/Granted day:2014-05-08
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