Invention Grant
- Patent Title: Sulfamide sodium channel inhibitors
- Patent Title (中): 磺酰胺钠通道抑制剂
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Application No.: US14383880Application Date: 2013-03-07
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Publication No.: US09051311B2Publication Date: 2015-06-09
- Inventor: Thomas Dineen , Charles Kreiman , Matthew Weiss , Stephanie Geuns-Meyer
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Elsa D. Lemoine
- International Application: PCT/US2013/029639 WO 20130307
- International Announcement: WO2013/134518 WO 20130912
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D417/12 ; C07D471/04 ; C07D487/04 ; A61K31/47 ; C07D417/14
Abstract:
The present invention provides compounds of Formula I, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention.
Public/Granted literature
- US20150018352A1 SULFAMIDE SODIUM CHANNEL INHIBITORS Public/Granted day:2015-01-15
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