Invention Grant
- Patent Title: Sulfur-containing bicyclic compound
- Patent Title (中): 含硫双环化合物
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Application No.: US14517229Application Date: 2014-10-17
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Publication No.: US09051339B2Publication Date: 2015-06-09
- Inventor: Nobuyuki Shiraishi , Hiroaki Hoshii , Wataru Hamaguchi , Eriko Honjo , Tomofumi Takuwa , Yuji Kondo , Takayuki Goto
- Applicant: Astellas Pharma Inc.
- Applicant Address: JP Chuo-ku
- Assignee: Astellas Pharma Inc.
- Current Assignee: Astellas Pharma Inc.
- Current Assignee Address: JP Chuo-ku
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2013-216332 20131017
- Main IPC: C07D495/04
- IPC: C07D495/04 ; A61K31/519 ; C07D495/10 ; C07D495/08 ; C07D513/04
Abstract:
A sulfur-containing bicyclic compound having a PAM action of GABAB, and it use for preventing and/or treating schizophrenia, CIAS, cognitive impairment, fragile X syndrome, autism spectrum disorder, spasticity, anxiety disorder, substance addiction, pain, fibromyalgia, or Charcot-Marie-Tooth disease. A pharmaceutical composition for preventing and/or treating schizophrenia, cognitive impairment associated with schizophrenia (CIAS), cognitive impairment, fragile X syndrome, autism spectrum disorder, spasticity, anxiety disorder, substance addiction, pain, fibromyalgia, Charcot-Marie-Tooth disease, or the like, which has a positive allosteric modulator (PAM action) of GABAB.
Public/Granted literature
- US20150111876A1 SULFUR-CONTAINING BICYCLIC COMPOUND Public/Granted day:2015-04-23
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