Invention Grant
US09051382B2 Human neutrophil gelatinase-associated lipocalin (hNGAL) muteins that bind hepcidin and nucleic acid encoding such
有权
人嗜中性粒细胞明胶酶相关脂质运载蛋白（hNGAL）突变蛋白，其结合铁调素和核酸编码
- Patent Title: Human neutrophil gelatinase-associated lipocalin (hNGAL) muteins that bind hepcidin and nucleic acid encoding such
- Patent Title (中): 人嗜中性粒细胞明胶酶相关脂质运载蛋白（hNGAL）突变蛋白，其结合铁调素和核酸编码
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Application No.: US13816808Application Date: 2011-08-16
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Publication No.: US09051382B2Publication Date: 2015-06-09
- Inventor: Stefan Trentmann , Gabriele Matschiner , Arne Skerra , Andreas Hohlbaum , Martin Huelsmeyer , Hendrik Gille , Hans-Juergen Christian , Kristian Jensen , Rachida Siham Bel Aiba
- Applicant: Stefan Trentmann , Gabriele Matschiner , Arne Skerra , Andreas Hohlbaum , Martin Huelsmeyer , Hendrik Gille , Hans-Juergen Christian , Kristian Jensen , Rachida Siham Bel Aiba
- Applicant Address: DE Freising-Wiehenstephan
- Assignee: PIERIS AG
- Current Assignee: PIERIS AG
- Current Assignee Address: DE Freising-Wiehenstephan
- Agency: Foley & Lardner, LLP
- International Application: PCT/EP2011/064086 WO 20110816
- International Announcement: WO2012/022742 WO 20120223
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C07K14/435 ; A61K38/16 ; A61K38/17 ; C07H21/04 ; C07K14/47 ; C07K16/26 ; C12N15/09 ; C12P21/02
Abstract:
The present invention relates to novel, specific-binding therapeutic and/or diagnostic proteins directed against Hepcidin, which proteins preferably are muteins of a lipocalin protein. The invention also relates to nucleic acid molecules encoding such proteins and to methods for generation and use of such proteins and nucleic acid molecules. Accordingly, the invention also is directed to pharmaceutical and/or diagnostic compositions comprising such a lipocalin proteins, including uses of these proteins.
Public/Granted literature
- US20130244955A1 BINDING PROTEINS FOR HEPCIDIN Public/Granted day:2013-09-19
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