Invention Grant
US09051390B2 Inhibition of prion propagation by receptor associated protein (RAP), its derivatives, mimetics and synthetic peptides
有权
受体相关蛋白（RAP），其衍生物，模拟物和合成肽抑制朊病毒繁殖
- Patent Title: Inhibition of prion propagation by receptor associated protein (RAP), its derivatives, mimetics and synthetic peptides
- Patent Title (中): 受体相关蛋白（RAP），其衍生物，模拟物和合成肽抑制朊病毒繁殖
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Application No.: US13265242Application Date: 2010-05-17
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Publication No.: US09051390B2Publication Date: 2015-06-09
- Inventor: Larisa Cervenakova , Oksana Yakovleva
- Applicant: Larisa Cervenakova , Oksana Yakovleva
- Applicant Address: US DC Washington
- Assignee: American National Red Cross
- Current Assignee: American National Red Cross
- Current Assignee Address: US DC Washington
- Agency: RatnerPrestia
- International Application: PCT/US2010/001455 WO 20100517
- International Announcement: WO2010/134970 WO 20101125
- Main IPC: C07K14/705
- IPC: C07K14/705 ; A61K38/17
Abstract:
A pharmaceutical formulation and method of treatment of prion disease include a RAP agent with a pharmaceutically acceptable carrier and/or excipient, and the administration of same to a subject suffering from or at risk of a prion disease. The RAP agent is an effective means for the prevention and/or treatment of various prion diseases regardless whether the disease is acquired by infection or by genetic mutation.
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