Invention Grant
- Patent Title: Oxidant resistant apolipoprotein A-1 and mimetic peptides
- Patent Title (中): 抗氧化剂载脂蛋白A-1和模拟肽
-
Application No.: US13967046Application Date: 2013-08-14
-
Publication No.: US09051393B2Publication Date: 2015-06-09
- Inventor: Jonathan D. Smith , Stanley L. Hazen
- Applicant: The Cleveland Clinic Foundation
- Applicant Address: US OH Cleveland
- Assignee: The Cleveland Clinic Foundation
- Current Assignee: The Cleveland Clinic Foundation
- Current Assignee Address: US OH Cleveland
- Agency: Honigman Miller Schwartz and Cohn LLP
- Agent Fernando Alberdi; Jonathan P. O'Brien
- Main IPC: C07K14/775
- IPC: C07K14/775 ; A61K31/22 ; A61K31/366 ; A61K31/40 ; A61K38/17 ; A61K38/00
Abstract:
A method of ameliorating one or more symptoms of an inflammatory condition in a subject comprises the step of administering to the subject a therapeutically effective amount of a polypeptide that is capable promoting cholesterol efflux from lipid loaded cells, the polypeptide consisting of the amino acid sequence of SEQ ID NO:1, in which each X in SEQ ID NO:1 is a phenylalanine amino acid.
Public/Granted literature
- US20140051624A1 OXIDANT RESISTANT APOLIPOPROTEIN A-1 AND MIMETIC PEPTIDES Public/Granted day:2014-02-20
Information query
